XenDesktop 7.6, Windows 2012 R2, Office 365

 

When opening any Office 365 application before opening Internet Explorer 11 (IE11) Office will fail with file permissions error.

It turns out Office 365 uses the temporary internet folder location from IE11 as its path to open temp files into. IE 11 has now got a new path for these files:

%userprofile%\AppData\Local\Microsoft\Windows\Temporary Internet Files\Content.IE5 – this Content.IE5 file does not exist until up have opened up IE11 first.

Even if you change the path in the user profile it ignores it and looks to use IE11 path regardless.

Solution:

Create group policy in IE11 (may have to load the IE11 admx files) which changes the path back to %userprofile%\AppData\Local\Microsoft\Windows\Temporary Internet Files

All works correctly once this applied.

 

Thanks to Andrew Hill – Senior Consultant, Experteq for the tip.